Recommended Cooling Times

Recommendations for post infusion cooling times are based on peak plasma concentrations, drug half life, potential interactions, recent trials and the experience of current users of the Paxman hair loss prevention system. The docetaxel post-infusion cooling time was based on a ramdomised comparative study.

It is recommended that patient’s hair is dampened with water, and hair conditioner (ph neutral) is applied to improve scalp contact and reduce the insulation effect of hair.

Where liver function and metabolism of the cytotoxic agent is impaired, scalp cooling may be less effective.

Results with Afro-Caribbean hair are less successful and it is advisable to increase cooling times by ½ to 1 hour.